New Plasmid-Mediated Quinolone Resistance Gene, qnrC , Found in a Clinical Isolate of Proteus mirabilis
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چکیده
منابع مشابه
Plasmid Pattern of Biofilm Producing Proteus mirabilis and Proteus vulgaris among Clinical Isolates in Kerman University Hospitals during 2011-2012
Background & Aims: Emergence of biofilm producing Proteus strains created a serious problem in the treatment of catheter-associated urinary tract infections. The aim of this research was to study biofilm production and plasmid pattern of proteus strains associated with Urinary tract infection. Methods: A total of 88 strains of Proteus were isolated from samples collected in hospitals of Kerman/...
متن کاملNovel plasmid-mediated 16S rRNA methylase, RmtC, found in a proteus mirabilis isolate demonstrating extraordinary high-level resistance against various aminoglycosides.
Proteus mirabilis ARS68, which demonstrated a very high level of resistance to various aminoglycosides, was isolated in 2003 from an inpatient in Japan. The aminoglycoside resistance of this strain could not be transferred to recipient strains Escherichia coli CSH-2 and E. coli HB101 by a general conjugation experiment, but E. coli DH5alpha was successfully transformed by electroporation with t...
متن کاملqnrA6 genetic environment and quinolone resistance conferred on Proteus mirabilis.
OBJECTIVES To determine the genetic location and environment of the qnrA6 gene in Proteus mirabilis PS16 where it was first described and to characterize the quinolone resistance qnrA6 confers. METHODS Transformation experiments and Southern blotting were performed for plasmid and genomic DNA of P. mirabilis PS16 to determine the qnrA6 location. Combinatorial PCRs with primers in qnrA6 and ge...
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Since ABRAHAM and CHAIN') reported the production of beta((l)-lactamase by Escherichia coli, penicillinases have been shown to play an important role in the resistance of organisms against (3lactam antibiotics2.3). In many cases, the 46lactamases of Gram-negative bacteria have been shown to be mediated by R plasmids'), in contrast to chromosomally encoded drug resistance'). 46-Lactamases of Pro...
متن کاملPlasmid-mediated quinolone resistance: a multifaceted threat.
Although plasmid-mediated quinolone resistance (PMQR) was thought not to exist before its discovery in 1998, the past decade has seen an explosion of research characterizing this phenomenon. The best-described form of PMQR is determined by the qnr group of genes. These genes, likely originating in aquatic organisms, code for pentapeptide repeat proteins. These proteins reduce susceptibility to ...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2009
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01400-08